Figure 6
SYNCRIP regulated colorectal cancer cell growth and migration via DNMT3A. (A) SW480 and HCT116 cells were infected with scr or SYNCRIP shRNA followed with or without DNMT3A plasmid, the protein level of DNMT3A was detected by Western blotting. (B, C) SW480 and HCT116 cells were infected with scr or SYNCRIP shRNA followed with or without DNMT3A plasmid, the proliferation and survival of SW480 and HCT116 cells were measured using CCK-8 assay (B) and trypan blue stain (C). ** P ˂ 0.01. (D, E) SW480 and HCT116 cells were infected with scr or SYNCRIP shRNA followed with or without DNMT3A plasmid, the motility of SW480 and HCT116 cells were analyzed using migration assay (D) and wound healing assay (E).
