Figure 8

Effects of SYNCRIP depletion on tumor growth in vivo. (A) Typical photos of tumors on day 28 from scr and on shRNA groups. (B) HE and Ki67 staining of sections from xenograft tumors. (C, D) SYNCRIP depletion significantly decreased the tumor size (C) and weight (D). **P ˂ 0.01, ***P ˂ 0.001. (E, F) Protein level of SYNCRIP and p16 in 3 representative tumors from each group were analyzed by western blotting (E) and quantified by densitometry analysis (F). *P ˂ 0.05, **P ˂ 0.01.