Figure 1
Identification and characterization of DEGs associated with the Wnt/β-Catenin signaling pathway. (A) Volcano plot, the DEGs between case and control samples in the GSE140973 dataset, identifying 780 up-regulated and 3943 down-regulated genes. The vertical lines correspond to 2.0-fold up and down, respectively, and the horizontal line represents a P value of 0.05. The orange points in the plot represent up-regulated DEGs, and the blue points represent down-regulated DEGs. (B) Venn diagram displaying the overlap of 26 genes between the 4723 DEGs and the 151 genes related to the Wnt/β-Catenin signaling pathway. (C) Bubble plots showing the top 10 significantly enriched in the KEGG pathways42,43,44. The size of the bubbles corresponds to the ratio of genes associated with that term or pathway. (D) Bubble plots showing the top 10 significantly enriched in the BP categories. The size of the bubbles corresponds to the ratio of genes associated with that term or pathway.
