Table 1 Baseline patient characteristics by stages of CKD.

From: Male sexual dysfunction in patients with chronic kidney disease: a cross-sectional study

 

Overall (N = 72)

CKD 1–2

(N = 39)

CKD 3a–3b

(N = 15)

CKD 4–5

(N = 18)

P value

Demographics

Age, y

43.94 ± 8.93

40.90 ± 8.10

50.20 ± 6.54

45.33 ± 9.65

0.001

Marital status (Married, %)

63 (87.50)

32 (82.10)

15 (100.00)

16 (88.90)

0.199

Weight, kg

68.86 ± 10.76

68.15 ± 12.12

70.37 ± 9.76

69.17 ± 8.59

0.791

Height, cm

168.71 ± 5.37

168.44 ± 5.80

168.60 ± 4.90

169.39 ± 5.00

0.825

BMI, kg/m2

24.18 ± 3.59

23.98 ± 3.98

24.75 ± 3.25

24.14 ± 3.08

0.780

Smoking status (%)

 Current smoker

12 (16.70)

5 (12.90)

3 (20.00)

4 (22.20)

0.032

 Ex-smoker

10 (13.90)

1 (2.60)

5 (33.30)

4 (22.20)

 

 Never

50 (69.40)

33 (84.60)

7 (46.70)

10 (55.60)

 

Drinking status (%)

 Current drinker

13 (18.10)

7 (17.90)

4 (26.70)

2 (11.10)

0.270

 Ex-drinker

10 (13.90)

3 (7.70)

2 (13.30)

5 (27.80)

 

 Never

49 (68.10)

29 (74.40)

9 (60.00)

11 (61.10)

 

Renal function

 Scr, μmol/L

246.72 ± 311.03

92.84 ± 18.06

143.61 ± 22.91

666.06 ± 391.12

< 0.001

 eGFR, mL/min/1.73 m2

62.22 ± 36.24

89.96 ± 19.11

49.97 ± 8.53

12.32 ± 8.66

< 0.001

 ACR, mg/L

1256.50

648.42

874.61

2892.25

< 0.001

 BuN, mmol/L

10.11 ± 8.65

5.21 ± 1.20

8.29 ± 5.17

22.22 ± 8.60

< 0.001

 BUA, μmol/L

410.63 ± 136.26

387.27 ± 102.33

440.77 ± 105.83

436.12 ± 205.36

0.289

Comorbidities (%)

 Hypertension

44 (61.10)

18 (46.20)

9 (60.00)

17 (94.40)

0.002

 Diabetes mellitus

11 (15.30)

2 (5.10)

2 (13.30)

7 (38.90)

0.004

 Chronic prostatitis

4 (5.60)

4 (10.30)

0 (0.00)

0 (0.00)

0.167

 Benign Prostate Hyperplasia

4 (5.60)

0 (0.00)

2 (13.30)

2 (11.10)

0.079

Medication regimen (%)

 ACEI/ARB

25 (34.70)

16 (41.00)

6 (40.00)

3 (16.70)

0.178

 CCB

18 (25.00)

1 (2.60)

5 (33.30)

12 (66.70)

 < 0.001

 β-blockers

9 (12.50)

1 (2.60)

0 (0.00)

8 (44.40)

 < 0.001

 ISA

24 (33.30)

18 (46.20)

3 (20.00)

3 (16.70)

0.042

 ULT

28 (38.90)

12 (30.80)

5 (33.30)

11 (61.10)

0.081

 SGLT2

2 (2.80)

1 (2.60)

1 (6.70)

0 (0.00)

0.506

 Other hypoglycemic drugs

5 (6.90)

2 (5.10)

1 (6.70)

2 (11.10)

0.71

Psychological factor

 Depression

7.12 ± 5.76

6.08 ± 4.94

5.07 ± 5.26

11.11 ± 6.19

0.002

 Anxious

3.24 ± 3.18

3.08 ± 3.24

2.73 ± 2.58

4.00 ± 3.51

0.476

  1. Significant values are in bold.
  2. Values are mean ± SD, n (%), or median (IQR).
  3. CKD: chronic kidney disease; BMI: body mass index; Scr: serum creatinine; eGFR: estimated glomerular filtration rate; ACR: albumin-to-creatinine ratio; BuN: urea nitrogen; BUA: blood uric acid; AECI/ARB: Angiotensin converting enzyme inhibitor, Angiotonin II receptor blocker; CCB: calcium channel blocker; β-blockers: Beta blockers; ISA: immunosuppressant; ULT: Urate-Lowering Therapy; SGLT2: sodium-dependent glucose transporters 2.