Figure 3
From: Targeting the ZMIZ1-Notch1 signaling axis for the treatment of tongue squamous cell carcinoma
The potential mechanism of ZMIZ1 regulation of invasion and metastasis in CAL-27 cells. (A) IHC was used to detect the protein expression of Notch1, Jagged1, MKP-1, SSBP2, MMP7 in TSCC tissues and adjacent non-tumor tissues. (B) qRT-PCR was used to detect the mRNA expression of Notch1, Jagged1, MKP-1, SSBP2 and MMP7 in CAL-27 cells. (C, D) Western Blot were used to detect the protein expression of Notch1, Jagged1, MKP-1, SSBP2 and MMP7 in CAL-27 cells. The data shown represent the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.
