Table 1 Laboratory characteristics of G carriers (rs10974944) and individuals without the variant who were diagnosed with polycythemia vera or essential thrombocythemia.

From: Exploring hematological alterations and genetics linked to SNV rs10974944 in myeloproliferative neoplasms among Amazon patients

Characteristics, Med, IQR

Polycythemia vera (n = 39)

Essential thrombocythemia (n = 61)

C/C (n = 12)

G carriers (n = 27)

p-value

C/C (n = 25)

G carriers (n = 36)

p-value

RBC (x million/mm3)

5.9 [4.7–6.6]

4.8 [4.2–6]

0.188

3.4 [3.1–3.9]

4.1 [3.3–4.7]

0.029

Ht (%)

49.8 [43–52.2]

48 [44.1–53.1]

0.866

36.9 [35–39.5]

40.4 [35.9–44.4]

0.025

Hb (g/dL)

15.7 [13.1–16.2]

15.4 [13.9–16.6]

0.958

12.1 [11.1–13.0]

13.5 [12–14.6]

0.004

MCV (pg)

83.6 [81.7–89.5]

93.7 [86.6–104.9]

0.030

106.5 [94.2113.2]

101.5 [90.5–112.6]

0.330

MCH (fL)

27.3 [24.1–29.4]

30.9 [28.1–33.3]

0.041

33.6 [31.5–37.5]

32.7 [29.8–36.6]

0.383

MCHC (g/dL)

32.1 [30.4–36.1]

32 [30.6–33.5]

0.816

32.4 [31.6–33.4]

32.5 [32.1–34.2]

0.597

WBC (x cells/mm3)

6670 [3835–11,118]

6540 [5190–12,580]

0.911

5260 [3810–7,455]

5410 [4233–6,670]

0.740

Platelets (x per mm3)

258,000 [176,250–440,000]

302,000 [0, 0–391]

0.0747

483,000 [368,500–704,500]

440,500 [323,750–1,119,000]

0.127

  1. RBC Red blood cell count, Ht Hematocrit, Hb Hemoglobin, MCV Mean corpuscular volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpuscular hemoglobin concentration, WBC White blood cell count. Reference values: RBC: 3.9–5.3 million/mm3, Ht: 36–48%, Hb: 12–16 g/dL, MCV: 80–100 fL, MCH: 27–33 pg, MCHC: 32–36 g/dL, WBC: 3,600–11,000 cells/mm3, Platelets: 150,000–400,000 per mm3.
  2. Significant values are in bold.
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