Table 2 Clinical characteristics of G carriers (rs10974944) and individuals without the variant who were diagnosed with polycythemia vera or essential thrombocythemia.
Clinical characteristics, n (%) | Polycythemia vera (n = 39) | Essential thrombocythemia (n = 61) | ||||
---|---|---|---|---|---|---|
C/C (n = 12) | G carriers (n = 27) | p-value | C/C (n = 25) | G carriers (n = 36) | p-value | |
Splenomegaly | ||||||
Yes | 2 (16.7) | 7 (25.9) | 0.692 | 4 (16) | 6 (16.6) | > 0.999 |
No | 10 (83.3) | 20 (74.1) | 21 (84) | 30 (83.3) | ||
Thrombotic events | ||||||
Yes | 0 (0.0) | 8 (29.6) | 0.041 | 3 (12) | 12 (58.3) | 0.073 |
No | 12 (100) | 19 (70.3) | 22 (88) | 24 (66.6) | ||
Hemorrhagic events | ||||||
Yes | 1 (9) | 0 (0) | 0.307 | 5 (20) | 9 (25) | 0.762 |
No | 11 (91) | 27 (100) | 20 (80) | 27 (75) |