Table 4 Haplotypes of JAK2 intron 12 presents in individuals with patients JAK2 V617 positive (JAK2 V617F+) and JAK2 V617 negative (JAK2 V617-).
Haplotype | rs10974944 | rs10815151 | rs10119004 | rs77375493 | JAK2 V617F+ | JAK2 V617F - | Chi–Square | Odds ratio (95% CI) | p-value |
|---|---|---|---|---|---|---|---|---|---|
1 | C | C | G | G | 6 (13.9%) | 17 (26.4%) | 9.025 | 0.3 (0.1–0.9) | 0.0024 |
2 | G | C | A | T | 20 (46.5%) | 1 (1.8%) | 57.79 | 19.6 (3.1–208) | < 0,0001 |
3 | G | C | A | G | 5 (11.6%) | 14 (26.4%) | 5.911 | 0.3 (0.1–1.1) | 0.0015 |
4 | C | T | A | G | 4 (9.3%) | 15 (28.3%) | 10.614 | 0.2 (0.08–0.8) | 0.0011 |
5 | C | C | A | G | 0 | 5 (9.4%) | 7.578 | 0.0 (0.0–0.8) | 0.0059 |
6 | C | T | A | T | 4 (9.3%) | 0 | 6.434 | 0.0 (0.08–0.8) | 0.0112 |
7 | C | C | G | T | 4 (9.3%) | 0 | 7.853 | 0.0 (0.08–0.8) | 0.0051 |
8 | G | T | A | G | 0 | 1 (1.8%) | 0.084 | 0.0 (0.08–11.09) | 0.7721 |
9 | G | C | G | G | 0 | 1 (1.8%) | 0.316 | 0.0 (0.08–11.09) | 0.5738 |
