Figure 4
Heat stress-mediated gene expression changes were extrapolated in contributing pathways integral to organ-level pathological manifestations. (A) Biological pathways were predicted based on the differentially expressed gene list obtained by comparing the brain tissues from control and heat stress groups. Significance level set at PFDR < 0.05, threshold at -log(p value) ~ 1.3, Log2 fold change > 1. The gradients of blue and red colors represented the up- and downregulations of the pathways’ respectively. (B) Biological pathways were predicted based on the differentially expressed gene list obtained by comparing the liver tissues from control and heat stress groups. Significance level set at PFDR < 0.05, threshold at -log(p value) ~ 1.3, Log2 fold change > 1. The gradients of blue and red colors represented the up- and downregulations of the pathways’ respectively. (C) Biological pathways were predicted based on the commonly differentially expressed gene list obtained by comparing both the brain and liver tissues from control and heat stress groups. Significance level set at PFDR < 0.05, threshold at -log(p value) ~ 1.3, Log2 fold change > 1. The gradients of blue and red colors represented the up- and downregulations of the pathways’ respectively.
