Figure 3

Sample cases of intra-individual difference. (A–D) Right and (E–H) left eyes of same subject. (A₁, E₁) Disc photographs. The arrowheads indicate the locations of the central retinal vascular trunk (CRVT). The dotted white lines indicate the locations of the OCT scans. (A₂, E₂) Infrared images with demarcated Bruch’s membrane opening (BMO) margin (red dots). The CRVT positions (yellow dot), the meridians of the longest externally oblique border (EOB, black dot), and the meridians of the maximal width of β-zone parapapillary atrophy (PPA, green dot) are marked on the same infrared images. (A₃, E₃) Measurement of lamina cribrosa (LC) / Bruch’s membrane opening (BMO) offset. The red arrows are drawn to show the direction and extent of CRVT (yellow dots) deviation from the BMO center (orange dots). (B, F) B-scan images. The red dots indicate the BMO margin and the yellow arrowheads indicate the CRVTs. (C, G) Sagittal and transverse sectional images of three-dimensional (3D) MRI. Asymmetric expansion is noted by the red arrowheads (D, H) 3D eyeball shapes are evaluated by optimal ellipsoid fitting. The blue dots indicate the location of the fovea, and the yellow dots that of the BMO. The red squares indicate the outermost protruded points, and the blue squares indicate the reciprocal innermost depressed points. Please note that the LC/BMO offset direction could differ between paired eyes of the same individual, and that it is determined by the 3D shape of the eyeball from the overgrowth to undergrowth directions (green arrows).