Table 1 Patients’ demographics.

Participants (n)

708

Age (years)^#

70.4 ± 6.9

Sex (male/female)

645/63

Smoking history (presence/absence/unknown)

684/20/4

Smoking index (pack-years)^#

N = 677, 55.3 ± 30

Emphysema (presence/absence/unknown)

326/381/1

Performance status

 0/1/2/3/4

226/378/84/16/4

Interstitial pneumonia

Clinical diagnosis of IIP (IPF/non-IPF/unknown)

406/294/8

HRCT pattern

 UIP pattern

275

 Possible UIP pattern

243

 Inconsistent with the UIP pattern

190

History of acute exacerbation (presence/absence/unknown)

11/689/8

Desaturation on exertion (presence/absence/unknown)

80/418/210

%FVC (%)^#

n = 441, 88.6 ± 19.14

%DLco (%)^#

n = 238, 64 ± 22.56

KL-6 (U/mL)^#

n = 564, 922.8 ± 985.25

SP-D (ng/mL)^#

n = 406, 135.6 ± 102.9

Treatment

 None

678

 Prednisolone

15

 Prednisolone + immunosuppressants

5

 Pirfenidone

7

 NAC

1

 Pirfenidone + NAC

1

 Pirfenidone + prednisolone

1

Lung cancer

Histopathologic type

 Small cell carcinoma

216

 Non-small cell carcinoma

492

  Adenocarcinoma

258

  Squamous cell carcinoma

173

  LCNEC

17

  LCC

9

  Others

35

EGFR mutation status

 Negative

274

 Positive

13

  L858R/deletion 21

9/4

 Not evaluated

421

ALK re-arrangement

 Negative

124

 Positive

2

 Not evaluated

582