Figure 3
From: Detection of clonal plasma cells in POEMS syndrome using multiparameter flow cytometry

Change in the size of clones detected by POEMS-flow after treatment. Six cases in which monoclonal PCs were identified at the time of diagnosis by POEMS-flow and the available post-treatment samples are evaluated. (A) Change in the size of clones detected using POEMS-flow after treatment. The size of the clones was significantly reduced after the treatment (Pā=ā0.031) in all six patients. (B) Change in serum vascular endothelial growth factor (VEGF) levels after treatment. Serum VEGF levels were significantly decreased after treatment (Pā=ā0.031) in all six patients. (C) Changes in the size of clones detected using POEMS-flow, serum VEGF levels, and the status of M-protein using immunofixation electrophoresis (IFE) for each patient after treatment.