Figure 3 | Scientific Reports

Figure 3

From: Detection of clonal plasma cells in POEMS syndrome using multiparameter flow cytometry

Figure 3

Change in the size of clones detected by POEMS-flow after treatment. Six cases in which monoclonal PCs were identified at the time of diagnosis by POEMS-flow and the available post-treatment samples are evaluated. (A) Change in the size of clones detected using POEMS-flow after treatment. The size of the clones was significantly reduced after the treatment (P = 0.031) in all six patients. (B) Change in serum vascular endothelial growth factor (VEGF) levels after treatment. Serum VEGF levels were significantly decreased after treatment (P = 0.031) in all six patients. (C) Changes in the size of clones detected using POEMS-flow, serum VEGF levels, and the status of M-protein using immunofixation electrophoresis (IFE) for each patient after treatment.

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