Table 1 Descriptive statistics for the overall sample.

From: Interaction of obesity and proteins associated with the NLRP3 inflammasome following mild traumatic brain injury

 

Obese BMI (n = 61)

Non-obese BMI (n = 129)

p

Age in years

45.2 ± 16.7

41.0 ± 17.8

0.13

Female sex

21 (34.4)

40 (31.0)

0.74

Diabetes

10 (16.4)

1 (0.8)

 < 0.001*

Hypertension

20 (32.8)

17 (13.2)

 < 0.001*

Hyperlipidemia

7 (11.5)

3 (2.3)

0.01*

Headache

0 (0.0)

1 (0.8)

1.00

Pulmonary disease

10 (16.4)

14 (10.9)

0.24

Renal disease

6 (10.0)

8 (6.2)

0.37

Anxiety

12 (19.7)

17 (13.2)

0.20

Depression

11 (18.0)

18 (14.0)

0.41

Sleep disorder

0 (0.0)

3 (2.3)

0.55

ASC (ng/mL)

1.00 ± 0.7

0.87 ± 0.4

0.17

Caspase-1 (pg/mL)

5185.35 ± 4114.3

6387.64 ± 5616.4

0.19

IL-18 (pg/mL)

876.24 ± 477.1

626.5 ± 295.0

0.002*

IL-1β (fg/mL)

203.33 ± 978.4

79.25 ± 127.6

0.44

RPQ at 2 weeks

23.0 ± 19.0

17.0 ± 14.2

0.03*

RPQ at 6 months

16.3 ± 17.7

13.4 ± 14.4

0.28

QOLIBRI-OS at 2 weeks

47.0 ± 26.1

53.8 ± 25.6

0.14

QOLIBRI-OS at 6 months

56.6 ± 28.2

63.1 ± 27.4

0.18

SF-12 physical at 2 weeks

32.1 ± 11.0

34.9 ± 11.7

0.18

SF-12 physical at 6 months

43.8 ± 11.7

46.8 ± 10.4

0.12

  1. ASC apoptotic speck-like protein, IL interleukin, RPQ Rivermead Post-concussion Questionnaire, QOLIBRI-OS Quality of Life after Brain Injury Overall Scale, SF-12 Short Form 12, ng/mL nanogram per milliliter, pg/mL picogram per milliliter, fg/mL femtogram per milliliter.
  2. *Statistically significant at p ≤ 0.05.
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