Table 3 Linear regression to predict outcomes at 2 weeks and 6 months post-mild traumatic brain injury.
Coefficient | 95% CI | p | |
|---|---|---|---|
RPQ 2 weeks | |||
Obese BMI (REF: non-obese BMI) | − 275.4 | − 475.0, − 75.6 | 0.01* |
Severely obese BMI (REF: non-obese BMI) | 270.7 | 66.9, 474.5 | 0.01* |
ASC | − 3.6 | − 14.2, 7.1 | 0.51 |
Caspase-1 | − 0.1 | − 5.2, 5.1 | 0.98 |
IL-18 | 5.0 | − 5.9, 15.8 | 0.36 |
IL-1β | 1.1 | − 4.0, 6.2 | 0.66 |
Obese BMI × ASC | 15.3 | − 16.5, 47.2 | 0.34 |
Severely obese BMI × ASC | 32.5 | 16.3, 48.7 | 0.00* |
Obese BMI × caspase-1 | 18.8 | 8.0, 29.6 | 0.00* |
Severely Obese BMI × caspase-1 | − 6.9 | − 23.5, 9.7 | 0.41 |
Obese BMI × IL-18 | 18.3 | − 4.5, 41.0 | 0.11 |
Severely obese BMI × IL-18 | − 27.5 | − 48.6, − 6.5 | 0.01* |
Obese BMI × IL-1β | 1.9 | − 4.7, 8.5 | 0.57 |
Severely obese BMI × IL-1β | − 2.8 | − 16.0, 10.4 | 0.68 |
Hypertension | − 2.6 | − 12.6, 7.5 | 0.61 |
Hyperlipidemia | 3.0 | − 10.0, 15.8 | 0.65 |
Diabetes | − 10.0 | − 19.4, − 0.7 | 0.04* |
RPQ 6 months | |||
Obese BMI (REF: non-obese BMI) | − 129.0 | − 353.6, 95.7 | 0.26 |
Severely obese BMI (REF: non-obese BMI) | 43.6 | − 209.6, 296.8 | 0.73 |
ASC | 3.8 | − 7.8, 15.5 | 0.51 |
Caspase-1 | 0.0 | − 4.4, 4.4 | 0.99 |
IL-18 | 6.1 | − 4.4, 16.6 | 0.25 |
IL-1β | 4.5 | 0.6, 8.5 | 0.03* |
Obese BMI × ASC | 10.2 | − 21.6, 41.9 | 0.53 |
Severely obese BMI × ASC | − 21.9 | − 51.0, 7.1 | 0.14 |
Obese BMI × caspase-1 | 15.2 | 4.8, 25.5 | 0.00* |
Severely obese BMI × caspase-1 | − 3.8 | − 18.2, 10.5 | 0.59 |
Obese BMI × IL-18 | 3.3 | − 19.7, 26.2 | 0.78 |
Severely obese BMI × IL-18 | 9.0 | − 18.0, 36.0 | 0.51 |
Obese BMI × IL-1β | − 3.7 | − 11.9, 4.6 | 0.38 |
Severely obese BMI × IL-1β | − 20.0 | − 36.2, − 3.9 | 0.02* |
Hypertension | 1.9 | − 7.6, 11.3 | 0.69 |
Hyperlipidemia | − 9.3 | − 19.4, 0.9 | 0.07 |
Diabetes | 1.6 | − 11.4, 14.6 | 0.81 |
QOLIBRI-OS 2 weeks | |||
Obese BMI (REF: non-obese BMI) | 240.4 | − 14.4, 495.2 | 0.06 |
Severely obese BMI (REF: non-obese BMI) | − 263.8 | − 771.7, 244.1 | 0.30 |
ASC | 0.7 | − 17.6, 18.9 | 0.94 |
Caspase-1 | − 1.7 | − 8.7, 5.3 | 0.63 |
IL-18 | − 3.7 | − 15.8, 8.5 | 0.55 |
IL-1β | − 0.4 | − 5.4, 4.5 | 0.86 |
Obese BMI × ASC | − 20.3 | − 66.7, 26.2 | 0.39 |
Severely obese BMI × ASC | − 41.8 | − 76.1, − 7.4 | 0.02* |
Obese BMI × caspase-1 | − 17.6 | − 31.4, − 3.7 | 0.01* |
Severely obese BMI × caspase-1 | 17.6 | − 18.1, 53.3 | 0.33 |
Obese BMI × IL-18 | − 13.8 | − 43.2, 15.6 | 0.35 |
Severely obese BMI × IL-18 | 5.5 | − 28.1, 39.0 | 0.75 |
Obese BMI × IL-1β | − 3.0 | − 10.0, 4.1 | 0.40 |
Severely obese BMI × IL-1β | 18.9 | 0.5, 37.3 | 0.05 |
Hypertension | 9.3 | − 6.7, 25.3 | 0.25 |
Hyperlipidemia | 6.5 | − 18.3, 31.2 | 0.60 |
Diabetes | − 11.9 | − 30.1, 6.3 | 0.20 |
QOLIBRI-OS 6 months | |||
Obese BMI (REF: non-obese BMI) | 82.0 | − 246.9, 410.8 | 0.62 |
Severely obese BMI (REF: non-obese BMI) | − 224.9 | − 589.4, 139.6 | 0.22 |
ASC | 8.0 | − 13.9, 29.9 | 0.47 |
Caspase-1 | − 2.5 | − 10.3, 5.3 | 0.52 |
IL-18 | − 3.9 | − 21.8, 14.0 | 0.67 |
IL-1β | − 7.5 | − 16.8, 1.8 | 0.11 |
Obese BMI × ASC | − 31.8 | − 83.4, 19.8 | 0.22 |
Severely obese BMI × ASC | 5.6 | − 40.8, 52.0 | 0.81 |
Obese BMI × caspase-1 | − 14.1 | − 32.8, 4.7 | 0.14 |
Severely obese BMI × caspase-1 | 10.8 | − 12.4, 33.9 | 0.36 |
Obese BMI × IL-18 | − 0.3 | − 36.0, 35.3 | 0.98 |
Severely obese BMI × IL-18 | − 2.6 | − 46.3, 41.1 | 0.90 |
Obese BMI × IL-1β | 6.4 | − 9.4, 22.1 | 0.42 |
Severely obese BMI × IL-1β | 41.3 | 15.0, 67.6 | 0.00* |
Hypertension | − 21.1 | − 40.0, − 2.5 | 0.03* |
Hyperlipidemia | 31.7 | 7.9, 55.4 | 0.01* |
Diabetes | − 6.1 | − 29.7, 17.5 | 0.61 |
SF-12 Physical 2 weeks | |||
Obese BMI (REF: non-obese BMI) | 19.5 | − 130.6, 169.6 | 0.80 |
Severely obese BMI (REF: non-obese BMI) | − 32.9 | − 204.0, 138.3 | 0.70 |
ASC | − 3.8 | − 11.5, 3.9 | 0.33 |
Caspase-1 | 0.5 | − 3.2, 4.2 | 0.79 |
IL-18 | 0.1 | − 9.1, 9.4 | 0.98 |
IL-1β | − 3.0 | − 5.4, − 0.7 | 0.01* |
Obese BMI × ASC | − 5.7 | − 21.0, 9.6 | 0.46 |
Severely obese BMI × ASC | − 6.2 | − 19.0, 6.7 | 0.34 |
Obese BMI × caspase-1 | − 2.6 | − 10.0, 4.8 | 0.49 |
Severely obese BMI × caspase-1 | 5.0 | − 6.8, 16.9 | 0.40 |
Obese BMI × IL-18 | 0.1 | − 15.9, 16.2 | 0.99 |
Severely obese BMI × IL-18 | − 5.9 | − 18.9, 7.2 | 0.37 |
Obese BMI × IL-1β | − 0.4 | − 3.9, 3.1 | 0.82 |
Severely obese BMI × IL-1β | 7.2 | − 1.6, 15.9 | 0.11 |
Hypertension | − 0.5 | − 6.4, 5.4 | 0.85 |
Hyperlipidemia | − 1.5 | − 10.4, 7.4 | 0.73 |
Diabetes | − 5.5 | − 10.3, − 0.8 | 0.02* |
SF-12 physical 6 months | |||
Obese BMI (REF: non-obese BMI) | − 35.6 | − 201.7, 130.3 | 0.67 |
Severely obese BMI (REF: non-obese BMI) | − 140.2 | − 232.9, − 47.6 | 0.00* |
ASC | − 2.1 | − 10.2, 6.0 | 0.60 |
Caspase-1 | − 2.2 | − 5.1, 0.6 | 0.13 |
IL-18 | − 4.9 | − 9.7, − 0.2 | 0.04* |
IL-1β | − 4.5 | − 7.1, − 1.9 | 0.00* |
Obese BMI × ASC | − 15.9 | − 35.6, 2.8 | 0.09 |
Severely obese BMI × ASC | − 4.2 | − 22.1, 13.6 | 0.64 |
Obese BMI × caspase-1 | − 2.3 | − 10.7, 6.1 | 0.59 |
Severely obese BMI × caspase-1 | 6.0 | − 0.5, 12.5 | 0.07 |
Obese BMI × IL-18 | 5.6 | − 11.1, 22.3 | 0.51 |
Severely obese BMI × IL-18 | 10.5 | − 4.0, 25.1 | 0.15 |
Obese BMI × IL-1β | 4.6 | − 3.5, 12.7 | 0.26 |
Severely obese BMI × IL-1β | 4.8 | − 3.0, 12.6 | 0.22 |
Hypertension | − 4.8 | − 12.1, 2.6 | 0.20 |
Hyperlipidemia | 7.5 | − 4.7, 19.7 | 0.22 |
Diabetes | − 12.8 | − 26.6, 1.1 | 0.07 |
