Figure 3 | Scientific Reports

Figure 3

From: Hematological and renal toxicity in mice after three cycles of high activity [177Lu]Lu-PSMA-617 with or without human α1-microglobulin

Figure 3

Animals treated with [177Lu]Lu-PSMA-617 had a decrease in blood cell counts. Blood cell counts during the course of the experiment. Percent of WBC (A), RBC (B) and PLT (C) compared to control animals. Number of WBC (D), RBC (E), and PLT (F) 6 weeks after last cycle. Dotted line represents when new cycle where administered. Data are presented as line charts (A–C) or scatter plots with mean (± SEM) (D–F). Statistical Statistical comparison between groups was made with one-way ANOVA with a Tukey's multiple comparisons post hoc test (D–F). Only significant differences are presented in the figure. *p < 0.05, *** p < 0.001, **** p < 0.0001.

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