Table 1 Clinical Outcome Measure Scores shown as mean ± standard deviation, and change from baseline shown as mean with 95% confidence interval in brackets.
Outcome measure | Baseline | 6 weeks | 12 weeks | 24 weeks | p-value (baseline to 24 weeks) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | N | Mean ± SD | Change^ | N | Mean ± SD | Change^ | N | Mean ± SD | Change^ | ||
MOXFQ walking | 53 ± 23 | 10 | 40 ± 21 | − 13 (− 24, − 2) | 10 | 23 ± 17 | − 30 (− 43, − 17) | 9 | 25 ± 18 | − 27 (− 41, − 13) | 0.002 |
MOXFQ pain | 52 ± 11 | 10 | 40 ± 15 | − 12 (− 18, − 5) | 10 | 29 ± 15 | − 23 (− 32, − 14) | 9 | 25 ± 18 | − 28 (− 41, − 15) | 0.001 |
MOXFQ social | 43 ± 18 | 10 | 36 ± 19 | − 7 (− 14, 0) | 10 | 26 ± 17 | − 18 (− 29, − 6) | 9 | 24 ± 17 | − 17 (− 28, − 6) | 0.006 |
EQ-5D-5L* | 0.70 [0.70, 0.73] | 9 | 0.74 [0.69, 0.79] | 0.02 [0.00, 0.18] | 9 | 0.77 [0.69, 0.82] | 0.07 [0.00, 0.27] | 8 | 0.77 [0.70, 0.96] | 0.16 [0.00, 0.46] | 0.03 |
EQ-VAS overall health | 71 ± 14 | 9 | 77 ± 9 | 7 (0, 14) | 9 | 80 ± 11 | 10 (2, 18) | 7 | 82 ± 11 | 14 (8, 20) | 0.001 |
VISA-A | 41 ± 22 | 10 | 47 ± 21 | 7 (1, 13) | 10 | 59 ± 16 | 19 (12, 26) | 9 | 61 ± 21 | 24 (13, 34) | < 0.001 |
VAS pain | 43 ± 23 | 10 | 36 ± 21 | − 7 (− 20, 6) | 10 | 26 ± 24 | − 17 (− 32, − 2) | 9 | 22 ± 19 | − 24 (− 44, − 3) | 0.03 |
SAS | 5.0 ± 2.4 | n/a | n/a | n/a | n/a | 8 | 6.6 ± 1.8 | 1.6 (0.4, 2.9) | 0.02 | ||
