Table 2 Ultrasound outcomes, shown individually for each radiologist (Rad), and UTC outcomes, reported as mean ± standard deviation, unless noted otherwise.
Outcome | Rad | Baseline | 6 weeks | 12 weeks | 24 weeks | P-value (baseline to 24 weeks) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Change mean (95% CI) | N | Change mean (95% CI) | N | Change mean (95% CI) | |||||||
Max AP Thickness, mm | 1 | 8.2 ± 1.5 | 5 | 8.5 ± 1.3 | 0.4 (− 0.1, 0.8) | 4 | 8.0 ± 1.6 | 0.0 (− 0.1, 0.1) | 2 | – | – | |
2 | 9.2 ± 1.6 | 8 | 9.2 ± 1.7 | 0.0 (− 0.3, 0.4) | 7 | 8.6 ± 2.1 | − 0.1 (− 0.5, 0.3) | 5 | 7.8 ± 1.3 | − 0.8 (− 1.3, − 0.2) | 0.02 | |
Lesion distance, mm | 1 | 39 ± 8 | 5 | 40 ± 7 | 2 (− 2, 5) | 4 | 36 ± 7 | − 2 (− 6, 3) | 2 | – | – | |
2 | 40 ± 17 | 8 | 45 ± 9 | 5 (− 8, 18) | 7 | 40 ± 10 | 0 (− 4, 4) | 5 | 43 ± 6 | 10 (− 15, 34) | 0.34 | |
Focal change,* mm | 1 | 0.0 [0.0, 3.6] | 5 | 0.3 [0.0, 3.6] | 0.0 [− 3.3, 3.0] | 4 | 1.5 [0.0, 3.7] | 0.1 [0.0, 3.0] | 2 | – | – | |
2 | 0.0 [0.0, 5.3] | 8 | 0.3 [0.0, 3.0] | 0.0 [− 3.2, 0.7] | 7 | 0.3 [0.0, 2.3] | 0.0 [− 4.6, 0.7] | 5 | 0.3[0.0, 3.0] | 0.0 [0.0, 0.0] | 1.00 | |
% thickness* | 1 | 0 [0.42] | 5 | 3 [0, 39] | 0 [− 39, 38] | 4 | 21 [0, 44] | 1 [0, 42] | 2 | – | – | |
2 | 0 [0, 54] | 8 | 0 [0, 35] | 0 [− 29, 7] | 7 | 0 [0, 38] | 0 [− 45, 10] | 5 | 0 [0, 0] | 0 [0, 0] | 1.00 | |
UTC fibre type^ (% disorganized) | – | 32 ± 16 | 7 | 29 ± 9 | − 3 (− 17, 11) | 7 | 26 ± 7 | − 2 (− 17, 14) | 6 | 27 ± 14 | − 3 (− 25, 19) | 0.73 |
