Table 3 The “gene–metabolite” network of the disease model.

From: Exploring the “gene–metabolite” network of ischemic stroke with blood stasis and toxin syndrome by integrated transcriptomics and metabolomics strategy

Gene/metabolite

Degree

Betweenness

Up/down

C3

3

12.5

Up

F2

3

6.5

Up

Estradiol

2

10

Down

F7

2

6

Up

Serotonin

2

4

Up

Gamma-aminobutyric acid

2

4

Down

Genistein

1

0

Up

l-Proline

1

0

Down

  1. Up: Compared with the NC group, the upregulated genes or metabolites in the disease group. Down: Compared with the NC group, the upregulated genes or metabolites in the disease group.