Table 6 Risk of presenting AP status for each risk factor combination.

From: Future perspective and clinical applicability of the combined use of plasma phosphorylated tau 181 and neurofilament light chain in Subjective Cognitive Decline and Mild Cognitive Impairment

Plasma p-tau181

Plasma NfL

Overall risk (%)

95% I.C

Lower

Upper

10.91

3.55

18.27

 + 

41.10

29.49

52.71

 + 

76.49

66.48

86.50

 + 

 + 

94.88

89.69

100

  1. Overall risk was derived from the following regression model equation: logit p (presenting AD pathology) = −2.10 + 174 × (plasma p-tau181) + 3.28 × (plasma NfL). For each risk factor, value was “1” if the condition was satisfied (+), “0” if the condition was not satisfied (–).