Table 3 Lipid peroxidation (TBARS) (µmol malondialdehyde g−1) in brain of rats treated with Nulanza in combination with Cytarabine or Etoposide.

From: Intake of oligoelements with cytarabine or etoposide alters dopamine levels and oxidative damage in rat brain

Tbars (µmol malondialdehyde g−1)

Treatment

Cortex

Striatum

Cerebellum-medulla oblongata

Control

7.69 ± 1.70

12.26 ± 1.39

8.62 ± 0.63

Nulanza

6.36 ± 1.42

8.48 ± 1.62

8.32 ± 1.67

Cytarabine

5.16 ± 0.97*

7.25 ± 1.97*

5.40 ± 0.54*a

Etoposide

7.40 ± 2.20

9.49 ± 3.01

7.47 ± 2.14

Nulanza + Cytarabine

6.18 ± 1.58

9.80 ± 3.19

7.44 ± 1.92

Nulanza + Etoposide

5.31 ± 1.00*

7.23 ± 2.12*

5.35 ± 0.82*a

  1. Cytarabine or OE + etoposide decreased lipid peroxidation in cortex: Anova *p < 0.05, **p < 0.02. In striatum and cerebellum/medulla-oblongata, we observed reduced lipid peroxidation by cytarabine and OE + etoposide *p < 0.01; and OE versus OE + etoposide Kruskal–Wallis **p < 0.02.
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