Table 4 Comparison of BIS values at the indicated intraoperative intervals according to group.

From: Effects of propofol, ketamine-propofol mixture in pediatric dental patients undergoing intravenous sedation: a clinical study

 

Propofol

1:3 Ketofol

1:4 Ketofol

p value*

Post hoc test

Preop

75.0 (73.0–81.0)

78.0 (75.0–81.0)

76.3 (75.0–78.0)

0.297

5 min

64.0 (53.0–72.0)

64.0 (56.0–70.0)

69.0 (65.0–74.0)

0.311

10 min

61.0 (53.0–69.0)

64.0 (60.0–71.0)

65.0 (60.0–68.0)

0.181

15 min

62.0 (51.0–67.0)

57.0 (48.0–66.0)

66.0 (62.0–69.0)

0.093

20 min

61.0 (48.0–65.0)

54.2 (45.0–64.0)

66.0 (63.0–72.0)

0.005

3–2; p = 0.007

25 min

55.0 (48.0–61.0)

57.0 (52.0–62.0)

65.0 (62.0–71.0)

 < 0.001

3–1; p = 0.031

3–2; p = 0.002

30 min

48.0 (43.0–63.0)

57.4 (49.0–67.0)

63.0 (61.0–71.0)

0.007

3–1; p < 0.001

35 min

52.0 (43.0–61.0)

61.4 (57.0–69.0)

64.6 (62.0–72.0)

 < 0.001

3–1; p = 0.005

40 min

59.0 (45.0–66.0)

64.0 (59.0–73.0)

65.3 (65.3–62.0)

0.009

2–1; p = 0.033

3–1; p < 0.001

  1. The results are presented as the medians (Q1–Q3).
  2. BIS bispectral index.
  3. *Kruskal‒Wallis test, Dunn’s test was performed for a post hoc analysis.
  4. Significant values are given in bold.