Figure 3 | Scientific Reports

Figure 3

From: Chemogenetic inhibition of the lateral hypothalamus effectively reduces food intake in rats in a translational proof-of-concept study

Figure 3

Effect of DCZ stimulation on the food intake of LH-hM4D(Gi) rats. (A): Effect of s.c. applied DCZ on SHAM-operated control rats; (B): Effect of s.c. applied DCZ on AAV5 LH-hM4D(Gi) rats; (C): Effect of s.c. applied DCZ on AAV9 LH-hM4D(Gi) rats; (D): Effect of p.o. applied DCZ on SHAM-operated control rats; (E): Effect of p.o. applied DCZ on AAV5 LH-hM4D(Gi) rats; (F): Effect of p.o. applied DCZ on AAV9 LH-hM4D(Gi) rats. Post-hoc Tukey HSD tests: * p < 0.05, ** p < 0.01, *** p < 0.001, compared to the vehicle-treated group.

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