Figure 1 | Scientific Reports

Figure 1

From: Effects of a high-fat diet on cognition and brain distribution of intranasal insulin in E3 and E4 male and female mice

Figure 1

Baseline elevated zero maze and rotorod. (A) There was an effect of diet on the time the mice spent in the anxiety-provoking open areas of elevated zero maze. ***p = 0.0026 (ANOVA). (B) Mice on a HFD moved less than mice on a STD in the elevated zero maze. **** p < 0.0001 (ANOVA). (C) Mice on a HFD fell quicker of the rotating rod than mice on a STD. ****p < 0.0001 (ANOVA)). HFD: high fat diet; STD: standard diet. E3 males: n = 9 HFD and n = 12 STD; E3 females: n = 19 HFD and n = 13 STD; E4 males: n = 7 HFD and n = 11 STD; E4 females: n = 15 HFD and n = 14 STD.

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