Figure 1

Down-regulation of PPARγ in OA cartilage. (A) Representative image of cartilage from patient with total knee replacement showing relatively normal cartilage (Con) and damaged cartilage (OA); protein expression (B) and quantification data of PPARγ (C); (D) mRNA expression of PPARγ. **P < 0.01, ***P < 0.001 versus Con.