Figure 5 | Scientific Reports

Figure 5

From: Efficacy of melatonin in alleviating disorders arising from repeated exposure to sevoflurane in males and females of the Wistar rats during preadolescence

Figure 5

The effect of melatonin on apoptosis markers in male and female rats with repeated exposure to sevoflurane. (A) One-way ANOVA analysis of Bax in male groups (***p < 0.001, male sevoflurane compared to a male control group, and #p < 0.05, sevoflurane + melatonin male group compared male sevoflurane group). (B) One-way ANOVA analysis of Bax in female groups (***p < 0.001, female sevoflurane compared to a female control group, and ##p < 0.01, sevoflurane + melatonin female group compared female sevoflurane group). (C) One-way ANOVA analysis of Bcl2 in male groups (*p < 0.05, sevoflurane male group compared to male group). (D) One-way ANOVA analysis of Bcl2 in female groups (**p < 0.01, sevoflurane female group compared to female control group, #p < 0.05, sevoflurane + melatonin female group compared to female sevoflurane group). (E) One-way ANOVA analysis of caspase-3 in male groups (***p < 0.001, male sevoflurane compared to a male control group, and #p < 0.05, sevoflurane + melatonin male group compared to male sevoflurane group). (F) One-way ANOVA analysis of caspase-3 in female groups (***p < 0.001, female sevoflurane compared to a female control group, and #p < 0.05, sevoflurane + melatonin female group compared to female sevoflurane group).

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