Figure 9 | Scientific Reports

Figure 9

From: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells

Figure 9

Fatty acid oxidation is not significantly changed in TAZ-KO cells. WT and TAZ-KO cells were incubated with tritium-labeled oleate to allow for import and subsequent oxidation. FAO rate was calculated based on the amount of tritium-labeled H+ released back into the medium as a result of oleate oxidation; n = 4. Data points represent means ± S.D. (error bars) for each individual biological replicate of each group. * 0.05 < p < 0.1, ** 0.01 < p < 0.05, *** 0.001 < p < 0.01.

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