Figure 4
Phylogenetic analysis and domain composition of TH1 proteins. (a) Phylogenic tree developed with the sequences of the bifunctional TMP synthase/HMP-P kinase from plants and Archaea and the sequences of TMP synthase from microorganisms. (b) Phylogenic tree developed with the sequences of the bifunctional TMP synthase/HMP-P kinase from plants and Archaea and the sequences of HMP-P kinase from microorganisms. The numbers at the branching points indicate the percentage of times that each branch topology was found during bootstrap analysis (n = 1000). The boxes represent predicted functional domains: red—HMP-P kinase, grey—TMP synthase, blue—HET kinase and pink—HET synthase.
