Table 1 Demographics and train-test cohort split of 5463 patients with gastric GISTs from the Surveillance, Epidemiology, and End Results (SEER) database for the years 2000 to 2020.
Variable | Whole population | Train cohort | Test cohort | p-value* |
|---|---|---|---|---|
Total patients | 5463 (100%) | 3824 (70%) | 1639 (30%) | Â |
Age_at_diagnosis | 64.0 [54, 73] | 63 [54, 73] | 64 [55, 72] | 0.554 |
Sex | ||||
 Male | 2650 (48.5%) | 1843(48.2%) | 807(49.2%) | 0.499 |
 Female | 2813 (51.5%) | 1981(51.8%) | 832(50.8%) | 0.499 |
Race | ||||
 White | 3409 (62.4%) | 2395(62.6%) | 1014(61.9%) | 0.615 |
 Black | 1234 (22.6%) | 853(22.3%) | 381(23.2%) | 0.468 |
 Others | 820 (15.0%) | 576(15.1%) | 244(14.9%) | 0.900 |
Marital_status_at_diagnosis | ||||
 Married | 3321 (60.8%) | 2320 (60.7%) | 1011 (61.1%) | 0.802 |
 Single | 2142 (39.2%) | 1504 (39.3%) | 638 (38.9%) | 0.802 |
Tumor_location | ||||
 Antrum or Pylorus | 622 (11.4%) | 435 (11.4%) | 187 (11.4%) | 1.000 |
 Body | 2971 (54.4%) | 2058 (53.8%) | 913 (55.7%) | 0.210 |
 Cardia or Fundus | 1870 (34.2%) | 1331 (34.8%) | 539 (32.9%) | 0.180 |
Tumor_grade | ||||
 Well/moderately differentiated | 3939 (72.1%) | 2757 (72.1%) | 1182 (72.1%) | 1.000 |
 Poorly differentiated/undifferentiated | 1524 (27.9%) | 1067 (27.9%) | 457 (27.9%) | 1.000 |
Tumor_size | ||||
 ≤ 2 cm | 697 (12.8%) | 491 (12.8%) | 206 (12.6%) | 0.817 |
 2–5 cm | 1782 (32.6%) | 1247 (32.6%) | 535 (32.6%) | 1.000 |
 5–10 cm | 1677 (30.7%) | 1181 (30.9%) | 496 (30.3%) | 0.671 |
 ≥ 10 cm | 1307 (23.9%) | 905 (23.7%) | 402 (24.4%) | 0.516 |
AJCC stage | ||||
 I | 3031 (55.5%) | 2132 (55.8%) | 899 (54.9%) | 0.558 |
 II | 734 (13.4%) | 501 (13.1%) | 233 (14.2%) | 0.287 |
 III | 676 (12.4%) | 487 (12.7%) | 189 (11.5%) | 0.233 |
 IV | 1022 (18.7%) | 704 (18.4%) | 318 (19.4%) | 0.410 |
Mitotic_rate | ||||
 ≤ 5/5 mm2 HPF | 4081 (74.7%) | 2853 (74.6%) | 1228 (74.9%) | 0.832 |
 > 5/5 mm2 HPF | 1382 (25.3%) | 971 (25.4%) | 411 (25.1%) | 0.832 |
Surgery | ||||
 Local excision | 608 (11.1%) | 409 (10.7%) | 199 (12.1%) | 0.131 |
 Radical_excision | 4010 (73.4%) | 2836 (74.2%) | 1174 (71.6%) | 0.056 |
 No_Surgery | 845 (15.5%) | 579 (15.1%) | 266 (16.2%) | 0.328 |
Regional_nodes_examined | ||||
 0 | 4177 (76.5%) | 2916 (76.3%) | 1261 (76.9%) | 0.610 |
 1–4 | 675 (12.4%) | 477 (12.5%) | 198 (12.1%) | 0.719 |
 > 4 | 611 (11.2%) | 431 (11.3%) | 180 (11.0%) | 0.792 |
Chemotherapy | ||||
 Yes | 2175 (39.8%) | 1497 (39.1%) | 678 (41.4%) | 0.132 |
 No/Unknown | 3288 (60.2%) | 2327 (60.9%) | 961 (58.6%) | 0.132 |
