Table 2 Univariate and multivariate Cox regression analyses of OS from the constructed nomogram.

Age_at_diagnosis

1.04

1.04–1.05

 < 0.005

1.04

1.04–1.05

 < 0.005

Sex

 Female

Reference

–

–

–

–

–

 Male

1.26

1.12–1.43

 < 0.005

1.40

1.23–1.60

 < 0.005

Race

 White

Reference

–

–

–

–

–

 Black

1.40

1.22–1.61

 < 0.005

1.43

1.24–1.65

 < 0.005

 Others

0.91

0.76–1.10

0.33

-

-

-

Marital_status_at_diagnosis

 Married

Reference

–

–

–

–

–

 Single

1.46

1.29–1.65

 < 0.005

1.33

1.17–1.52

 < 0.005

Tumor_location

 Antrum or Pylorus

Reference

–

–

–

–

–

 Body

1.28

1.03–1.58

0.02

1.11

0.90–1.39

0.33

 Cardia or Fundus

1.57

1.26–1.95

 < 0.005

1.17

0.93–1.46

0.17

Tumor_grade

 Well/moderately differentiated

Reference

–

–

–

–

–

 Poorly differentiated/undifferentiated

2.09

1.84–2.36

 < 0.005

1.34

1.13–1.59

 < 0.005

Tumor_size

 ≤ 2 cm

Reference

–

–

–

–

–

 2–5 cm

1.46

1.10–1.93

0.01

1.28

0.96–1.70

0.09

 5–10 cm

2.04

1.55–2.68

 < 0.005

1.68

1.26–2.24

 < 0.005

 ≥ 10 cm

3.11

2.37–4.09

 < 0.005

1.97

1.43–2.70

 < 0.005

AJCC* stage

 I

Reference

–

–

–

–

–

 II

1.34

1.10–1.64

 < 0.005

1.17

0.90–1.51

0.24

 III

1.86

1.55–2.23

 < 0.005

1.40

1.03–1.90

0.03

 IV

3.47

3.00–4.01

 < 0.005

1.81

1.42–2.32

 < 0.005

Mitotic_rate

 ≤ 5/5 mm² HPF*

Reference

–

–

–

–

–

 > 5/5 mm² HPF*

1.69

1.49–1.92

 < 0.005

0.89

0.71–1.11

0.31

Surgery

 Local excision

Reference

–

–

–

–

–

 Radical_excision

1.15

0.93–1.43

0.20

–

–

–

 No_Surgery

4.18

3.31–5.28

 < 0.005

2.24

1.87–2.69

 < 0.005

Regional_nodes_examined

 0

Reference

–

–

–

–

–

 1–4

0.93

0.77–1.11

0.43

–

–

–

 > 4

1.09

0.90–1.30

0.38

–

–

–

Chemotherapy

 Yes

1.57

1.39–1.77

 < 0.005

0.95

0.82–1.10

0.52

 No/Unknown

Reference

–

–

–

–

–