Table 1 Summary of PBC and EHAIDs.
Diseases | GWAS PMIDa | Case number | Control number | Web Sourceb | MR study | |
|---|---|---|---|---|---|---|
PBC on EHAID | EHAID on PBC | |||||
Primary biliary cholangitis | 34033851 | 8021 | 16,489 | GWAS-catalog: GCST90061440 | ||
Rheumatoid arthritis | 24390342 | 14,361 | 42,923 | GWAS-catalog: GCST002318 | Positive | Positive |
Systemic lupus erythematosus | 26502338 | 5201 | 9066 | GWAS-catalog: GCST003156 | Positive | Positive |
Sjögren's syndrome | 28076899 | 585 | 1546 | GWAS-catalog: GCST012796 | Positive | Positive |
Systemic sclerosis | 31672989 | 9095 | 17,584 | GWAS-catalog: GCST009131 | Positive | Positive |
Autoimmune thyroid disease | 32581359 | 30,234 | 725,172 | deCODE | Positive | Null |
Autoimmune hyperthyroidism | FinnGen | 1828 | 279,855 | FinnGen-R9: AUTOIMMUNE_HYPERTHYROIDISM | Positive | Null |
Graves' disease | FinnGen | 2836 | 374,441 | FinnGen-R9: E4_GRAVES_STRICT | Positive | Null |
Autoimmune hypothyroidism | FinnGen | 40,926 | 274,069 | FinnGen-R9: E4_HYTHY_AI_STRICT | Positive | Positive |
Inflammatory bowel disease | 26192919 | 31,665 | 33,977 | MR-base: ieu-a-294 | Positive | Positive |
Crohn's disease | 26192919 | 17,897 | 33,977 | MR-base: ieu-a-12 | Null | Positive |
Ulcerative colitis | 26192919 | 13,768 | 33,977 | MR-base: ieu-a-970 | Positive | Positive |
Celiac disease | 22057235 | 11,812 | 11,837 | GWAS-catalog: GCST005523 | Null | Positive |
Multiple sclerosis | 31604244 | 47,429 | 68,374 | MR-base: ieu-b-18 | Positive | Null |
Psoriasis | 34927100 | 15,967 | 28,194 | GWAS-catalog: GCST90019016 | Positive | Null |
