Table 1 Baseline.

From: Using blood routine indicators to establish a machine learning model for predicting liver fibrosis in patients with Schistosoma japonicum

Variable, median (IQR)

All (n = 1049)

Non-fibrosis group (n = 768)

Fibrosis group (n = 281)

P-value

Age (years)

62 (51, 71)

59 (49, 69)

67 (58, 73)

 < 0.001

Sex, n (%)

0.471

 Female

344 (32.80)

247 (32.16)

97 (34.52)

 

 Male

705 (67.81)

521 (67.84)

184 (65.48)

TT (s)

18.766 (17.901, 19.006)

18.756 (17.869, 18.766)

18.766 (18.100, 19.600)

 < 0.001

Fibrinogen (g/L)

2.492 (2.399, 2.906)

2.535 (2.492, 2.964)

2.492 (2.070, 2.731)

 < 0.001

Prothrombin activity (%)

133.57 (116.23, 144.50)

138.90 (120.81, 144.50)

117.46 (87.90, 142.03)

 < 0.001

INR

1.057 (1.052, 1.057)

1.056 (1.053, 1.057)

1.057 (1.050, 1.160)

 < 0.001

PT (s)

11.591 (11.529, 11.593)

11.589 (11.531, 11.591)

11.591 (11.500, 12.700)

 < 0.001

APTT (s)

25.130 (22.710, 25.437)

24.300 (22.703,25.437)

25.437 (22.900, 28.100)

 < 0.001

Glucose (mmol/L)

5.320 (4.940, 5.850)

5.340 (4.950, 5.820)

5.280 (4.920, 5.940)

0.992

LDL (mmol/L)

3.216 (2.590, 3.870)

3.310 (2.720, 3.950)

2.900 (2.240, 3.430)

 < 0.001

HDL (mmol/L)

1.330 (1.120, 1.590)

1.320 (1.100, 1.560)

1.380 (1.150, 1.650)

0.005

Total cholesterol (mmol/L)

4.850 (4.220, 5.540)

4.951 (4.320, 5.670)

4.600 (3.961, 5.260)

 < 0.001

Triglycerides (mmol/L)

1.180 (0.860, 1.690)

1.260 (0.930, 1.820)

0.970 (0.700, 1.340)

 < 0.001

Uric acid (μmol/L), mean ± SD

349.532 ± 96.554

346.677 ± 89.926

357.417 ± 112.477

0.154

Creatinine (μmol/L), mean ± SD

70.923 ± 33.009

68.948 ± 23.433

76.359 ± 50.364

0.019

Urea nitrogen (mmol/L), mean ± SD

5.354 ± 4.229

5.185 ± 3.279

5.820 ± 6.099

0.100

Glutamyl transpeptidase (U/L)

29.000 (19.000, 53.000)

26.000 (18.000, 41.000)

52.000 (27.000, 103.000)

 < 0.001

Alkaline phosphatase (U/L)

74.000 (60.000, 91.000)

70.000 (58.000, 84.000)

85.000 (69.000, 121.000)

 < 0.001

Total bile acid (ÎĽmol/L)

3.000 (2.570, 6.200)

2.570 (2.400, 4.700)

6.000 (2.900, 13.900)

 < 0.001

AST (U/L)

24.000 (20.000, 31.000)

22.000 (18.000, 26.000)

33.000 (28.000, 45.000)

 < 0.001

ALT (U/L)

24.000 (18.000, 32.000)

21.000 (16.000, 27.000)

32.000 (25.000, 43.000)

 < 0.001

Globulin (g/L)

26.000 (23.800, 28.700)

25.600 (23.700, 28.000)

26.900 (24.400, 32.000)

 < 0.001

Albumin (g/L)

44.000 (40.600, 46.100)

44.800 (41.500, 46.300)

41.800 (36.200, 45.700)

 < 0.001

Indirect bilirubin (ÎĽmol/L)

9.300 (7.000, 12.500)

8.800 (6.700, 11.500)

11.500 (8.200, 14.100)

 < 0.001

Platelet distribution width (%)

16.000 (15.872, 16.500)

15.900 (15.872, 16.300)

16.300 (15.872, 16.900)

 < 0.001

Plateletcrit (ng/mL)

0.210 (0.166, 0.218)

0.210 (0.190, 0.230)

0.148 (0.110, 0.193)

 < 0.001

Platelets (*109/L)

175.000 (137.000, 216.000)

197.000 (163.000, 227.000)

109.000 (79.000, 140.000)

 < 0.001

RDW-CV (%)

13.300 (12.500, 13.802)

13.200 (12.400, 13.802)

13.600 (12.900, 14.311)

 < 0.001

RDW-SD (%)

44.000 (42.170, 46.300)

43.600 (41.747, 45.533)

46.000 (43.300, 49.900)

 < 0.001

MCHC (g/L)

328.000 (321.000, 334.000)

328.000 (321.000, 334.000)

327.000 (318.000, 334.000)

0.388

MCH (pg)

30.900 (29.800, 32.100)

30.800 (29.800, 31.800)

31.500 (29.900, 32.700)

 < 0.001

MCV (fl)

94.500 (90.600, 98.200)

94.000 (90.600, 97.400)

96.000 (90.900, 99.600)

 < 0.001

HCT (%)

41.933 (38.725, 44.600)

42.500 (39.900, 45.000)

39.000 (34.500, 43.100)

 < 0.001

HB (g/L)

138.000 (125.000, 149.000)

140.000 (130.000, 150.000)

126.000 (111.000, 142.000)

 < 0.001

Red blood cells (*1012/L)

4.480 (4.070, 4.840)

4.580 (4.240, 4.920)

4.110 (3.560, 4.590)

 < 0.001

Basophils (*109/L)

0.010 (0.010, 0.020)

0.010 (0.010, 0.020)

0.010 (0.010, 0.020)

 < 0.001

Eosinophils (*109/L)

0.130 (0.080, 0.210)

0.140 (0.090, 0.220)

0.120 (0.070, 0.180)

 < 0.001

Monocytes (*109/L)

0.320 (0.250, 0.400)

0.330 (0.260, 0.400)

0.270 (0.210, 0.370)

 < 0.001

Lymphocytes (*109/L)

1.650 (1.240, 2.070)

1.730 (1.380, 2.110)

1.250 (0.850, 1.790)

 < 0.001

Neutrophils (*109/L)

3.120 (2.430, 3.960)

3.300 (2.680, 4.190)

2.430 (1.850, 3.260)

 < 0.001

White blood cell (*109/L)

5.400 (4.400, 6.430)

5.610 (4.850, 6.690)

4.290 (3.340, 5.470)

 < 0.001

  1. TT thrombin time, INR international normalized ratio, PT prothrombin time, APTT activated partial thromboplastin time, LDL low-density lipoprotein, HDL high-density lipoprotein, AST aspartate aminotransferase, ALT alanine aminotransferase, RDW-CV red cell distribution width-coefficient of variation count, RDW-SD red cell distribution width-standard deviation, MCHC mean corpuscular hemoglobin concentration, MCH mean corpuscular hemoglobin, MCV mean corpuscular volume, HCT hematocrit, HB hemoglobin.
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