Figure 1

Single-cell clustering dimension reduction and cell annotation. (A) Violin plots of gene number (nFeature_RNA), transcript number (nCount_RNA), erythrocyte gene percentage (percent. HB), mitochondrial gene percentage (percent. MT), ribosome gene percentage (percent. Ribo) for each sample after single-cell data filtering. Primary HCC (up), relapsed HCC (down). (B). UMAP plots of the distribution of primary and relapsed HCC samples. (C) UMAP plots of the distribution of 17 cell subpopulations. (D) UMAP plots of each cell subpopulation after annotation. (E) Point plots of the top 5 marker genes expression of the subpopulations after CNV annotation. (F) Proportions of the cell subpopulations after CNV annotation in each sample.