Figure 3 | Scientific Reports

Figure 3

From: Multi-omics analysis of macrophage-associated receptor and ligand reveals a strong prognostic signature and subtypes in hepatocellular carcinoma

Figure 3

Construction of molecular subtypes based on macrophage receptor ligand genes. (A) Univariate Cox regression to identify moderators associated with prognosis. (B) Clustering analysis of TCGA-LIHC and GSE14520 patients based on the screened regulatory genes using the NMF algorithm. (C) The PCA of clusters demonstrates good heterogeneity. (D,E) Kaplan–Meier survival curves of OS in three clusters. TCGA-LIHC cohort(D), GSE14520 cohort(E). (F) Heatmap of the correlation between clinical characteristics and gene expression for the three subgroups.

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