Figure 5 | Scientific Reports

Figure 5

From: Multi-omics analysis of macrophage-associated receptor and ligand reveals a strong prognostic signature and subtypes in hepatocellular carcinoma

Figure 5

Immunological characteristics of molecular subtypes and analysis of different drug sensitivity. (A) Differences in twenty-two immune cell scores among molecular subtypes in the TCGA-LIHC cohort. (B,C) Expression levels and differential analysis of HLA (B) and immune checkpoints (C) in three molecular subtypes. (D) ESTIMATE algorithm to assess the overall TME landscape across subtypes, including stromal, immune, and estimate scores. (E) Drug effectiveness of molecular subtypes. Bleomycin (left), cisplatin (middle), and doxorubicin (right). (ns, not significant; p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001).

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