Table 1 IC50 values of adult B. malayi in the three drug environments (fenbendazole, ivermectin, and albendazole).

From: An automated, high-resolution phenotypic assay for adult Brugia malayi and microfilaria

Extracted parameters for adult Brugia malayi

Estimated IC50 (μM)

  
 

Fenbendazole

Ivermectin

Albendazole

Centroid velocity

99.73

2.768

291

Angular velocity

107.3

2.468

290.3

Δ Eccentricity

104.3

2.408

298.6

Δ Extent

102.9

2.368

291.1

Δ Euler number

108.1

3.04

333.2

Path curvature

139.1

13.39

342.5