Table 2 Comparison of resistance rates of H. influenzae isolates before and during the COVID-19 pandemic.

From: Impact of the COVID-19 pandemic on Haemophilus influenzae infections in pediatric patients hospitalized with community acquired pneumonia

Antibiotics

No. (%) of resistant isolates

Total (n = 986)

2018 (n = 240)

2019 (n = 333)

2020 (n = 83)

2021 (n = 186)

2022 (n = 144)

Ampicillin

847 (85.9)

210 (87.5)

287 (86.2)

69 (83.1)

157 (84.4)

124 (86.1)

Amoxicillin-clavulanate

189 (19.2)

61 (25.4)

54 (16.2)a

8 (9.6)a

42 (22.6)

24 (16.7)

Cefaclor

372 (37.7)

111 (46.3)

120 (36.0)a

13 (15.7)a, b

69 (37.1)

59 (41.0)

Cefuroxime

365 (37.0)

107 (44.6)

118 (35.4)a

13 (15.7)a, b

69 (37.1)

58 (40.3)

Cefotaxime

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Rifampicin

1 (0.1)

1 (0.4)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Ofloxacin

2 (0.2)

1 (0.4)

0 (0.0)

1 (1.2)

0 (0.0)

0 (0.0)

Tetracycline

62 (6.3)

18 (7.5)

24 (7.2)

2 (2.4)

10 (5.4)

8 (5.6)

Chloramphenicol

61 (6.2)

17 (7.1)

17 (5.1)

5 (6.0)

11 (5.9)

11 (7.6)

Trimethoprim-sulfamethoxazole

665 (67.4)

183 (76.3)

219 (65.8)a

52 (62.7)a

115 (61.8)a

96 (66.7)a

MDR isolates

379 (38.4)

120 (50.0)

117 (35.1)a

17 (20.5) a, b

73 (39.2)a

52 (36.1)a

  1. a: P < 0.05 Versus 2018; b: P < 0.05 Versus 2019.