Table 3 APR-DRG score, comorbidities, and clinical conditions comparing patients living in neighborhoods of income at the lowest and highest quartiles who underwent isolated TAVR.
Low SES (n = 12,355), n (%) | High SES (n = 15,212), n (%) | p-value | |
|---|---|---|---|
APR-DRG risk of mortality subclass | |||
Class 1 | 1346 (10.89%) | 1920 (12.62%) | < 0.01 |
Class 2 | 5616 (45.46%) | 7120 (46.81%) | 0.03 |
Class 3 | 4269 (34.55%) | 4927 (32.39%) | < 0.01 |
Class 4 | 1124 (9.1%) | 1245 (8.18%) | 0.01 |
Comorbidities | |||
Acquired immune deficiency syndrome | 11 (0.09%) | 22 (0.14%) | 0.22 |
Alcohol abuse | 147 (1.19%) | 194 (1.28%) | 0.55 |
Autoimmune conditions | 537 (4.35%) | 764 (5.02%) | 0.01 |
Lymphoma | 100 (0.81%) | 170 (1.12%) | 0.01 |
Leukemia | 87 (0.7%) | 153 (1.01%) | 0.01 |
Metastatic cancer | 65 (0.53%) | 123 (0.81%) | 0.01 |
Solid tumor without metastasis, in situ | 2 (0.02%) | 5 (0.03%) | 0.47 |
Solid tumor without metastasis, malignant | 294 (2.38%) | 464 (3.05%) | < 0.01 |
Cerebrovascular disease | 295 (2.39%) | 353 (2.32%) | 0.72 |
Heart Failure | 10 (0.08%) | 6 (0.04%) | 0.21 |
Dementia | 531 (4.3%) | 641 (4.21%) | 0.74 |
Depression | 915 (7.41%) | 1221 (8.03%) | 0.06 |
Diabetes without chronic complications | 2156 (17.45%) | 2213 (14.55%) | < 0.01 |
Diabetes with chronic complications | 3012 (24.38%) | 2924 (19.22%) | < 0.01 |
Drug abuse | 50 (0.4%) | 39 (0.26%) | 0.03 |
Complicated hypertension | 8241 (66.7%) | 9617 (63.22%) | < 0.01 |
Uncomplicated hypertension | 2816 (22.79%) | 3823 (25.13%) | < 0.01 |
Moderate to advanced liver disease | 15 (0.12%) | 32 (0.21%) | 0.08 |
Chronic pulmonary disease | 3795 (30.72%) | 3602 (23.68%) | < 0.01 |
Obesity | 2763 (22.36%) | 2617 (17.2%) | < 0.01 |
Paralysis | 213 (1.72%) | 217 (1.43%) | 0.05 |
Peripheral vascular disease | 2776 (22.47%) | 3253 (21.38%) | 0.03 |
Advanced renal failure | 475 (3.84%) | 470 (3.09%) | < 0.01 |
Hypothyroidism | 2380 (19.26%) | 3104 (20.4%) | 0.02 |
Other thyroid disorders | 133 (1.08%) | 238 (1.56%) | < 0.01 |
Coronary artery disease | 8551 (69.21%) | 10,161 (66.8%) | < 0.01 |
Left ventricle dysfunction | 28 (0.23%) | 39 (0.26%) | 0.71 |
Pulmonary hypertension | 2084 (16.87%) | 2334 (15.34%) | < 0.01 |
Endocarditis | 29 (0.23%) | 39 (0.26%) | 0.81 |
Atrial fibrillation | 4447 (35.99%) | 5861 (38.53%) | < 0.01 |
Atrial flutter | 409 (3.31%) | 553 (3.64%) | 0.15 |
Ventricular fibrillation | 80 (0.65%) | 77 (0.51%) | 0.13 |
Ventricular flutter | 2 (0.02%) | 1 (0.01%) | 0.59 |
Sick sinus syndrome | 351 (2.84%) | 446 (2.93%) | 0.66 |
First-degree atrioventricular block | 633 (5.12%) | 1049 (6.9%) | < 0.01 |
Second-degree atrioventricular block | 145 (1.17%) | 227 (1.49%) | 0.02 |
Complete atrioventricular block | 1017 (8.23%) | 1449 (9.53%) | < 0.01 |
Carotid artery disease | 13 (0.11%) | 14 (0.09%) | 0.85 |
Hyperlipidemia | 8801 (71.23%) | 11,356 (74.65%) | < 0.01 |
Anemia | 845 (6.84%) | 878 (5.77%) | < 0.01 |
Thrombocytopenia | 1161 (9.4%) | 1574 (10.35%) | 0.01 |
Sleep apnea | 2059 (16.67%) | 2421 (15.92%) | 0.09 |
Tobacco use | 4977 (40.28%) | 6098 (40.09%) | 0.75 |
Previous MI | 1595 (12.91%) | 1723 (11.33%) | < 0.01 |
Previous CVA | 2640 (21.37%) | 3368 (22.14%) | 0.12 |
Previous CABG | 2023 (16.37%) | 2228 (14.65%) | < 0.01 |
Previous PCI | 1490 (12.06%) | 1750 (11.5%) | 0.16 |
Previous valve replacement | 397 (3.21%) | 463 (3.04%) | 0.42 |
