Table 5 APR-DRG score, comorbidities, and clinical conditions comparing patients living in neighborhoods of income at the lowest and highest quartiles who underwent isolated SAVR.

From: Socioeconomic disparity in transcatheter and surgical aortic valve replacement: a population study of National Inpatient Sample from 2015 to 2020

 

Low SES (n = 10,029), n (%)

High SES (n = 10,811), n (%)

p-value

APR-DRG risk of mortality subclass

 Class 1

1500 (14.96%)

1926 (17.82%)

 < 0.01

 Class 2

2980 (29.71%)

3571 (33.03%)

 < 0.01

 Class 3

3161 (31.52%)

3366 (31.13%)

0.56

 Class 4

2388 (23.81%)

1948 (18.02%)

 < 0.01

Comorbidities

 Acquired immune deficiency syndrome

66 (0.66%)

27 (0.25%)

 < 0.01

 Alcohol abuse

358 (3.57%)

292 (2.7%)

 < 0.01

 Autoimmune conditions

311 (3.1%)

338 (3.13%)

0.94

 Lymphoma

37 (0.37%)

61 (0.56%)

0.04

 Leukemia

23 (0.23%)

31 (0.29%)

0.50

 Metastatic cancer

25 (0.25%)

35 (0.32%)

0.37

 Solid tumor without metastasis, in situ

2 (0.02%)

2 (0.02%)

1.00

 Solid tumor without metastasis, malignant

100 (1%)

128 (1.18%)

0.21

 Cerebrovascular disease

199 (1.98%)

154 (1.42%)

 < 0.01

 Heart Failure

3 (0.03%)

6 (0.06%)

0.51

 Dementia

103 (1.03%)

76 (0.7%)

0.01

 Depression

986 (9.83%)

895 (8.28%)

 < 0.01

 Diabetes without chronic complications

1290 (12.86%)

983 (9.09%)

 < 0.01

 Diabetes with chronic complications

1591 (15.86%)

1343 (12.42%)

 < 0.01

 Drug abuse

476 (4.75%)

173 (1.6%)

 < 0.01

 Complicated hypertension

3645 (36.34%)

3214 (29.73%)

 < 0.01

 Uncomplicated hypertension

4100 (40.88%)

4770 (44.12%)

 < 0.01

 Moderate to advanced liver disease

10 (0.1%)

12 (0.11%)

0.83

 Chronic pulmonary disease

2348 (23.41%)

1698 (15.71%)

 < 0.01

 Obesity

2670 (26.62%)

2369 (21.91%)

 < 0.01

 Paralysis

147 (1.47%)

93 (0.86%)

 < 0.01

 Peripheral vascular disease

2468 (24.61%)

3195 (29.55%)

 < 0.01

 Advanced renal failure

226 (2.25%)

117 (1.08%)

 < 0.01

 Hypothyroidism

1186 (11.83%)

1375 (12.72%)

0.05

 Other thyroid disorders

109 (1.09%)

181 (1.67%)

 < 0.01

 Coronary artery disease

4016 (40.04%)

10,161 (66.8%)

 < 0.01

 Left ventricle dysfunction

45 (0.45%)

38 (0.35%)

0.27

 Pulmonary hypertension

1458 (14.54%)

1194 (11.04%)

 < 0.01

 Endocarditis

1015 (10.12%)

808 (7.47%)

 < 0.01

 Atrial fibrillation

4108 (40.96%)

4869 (45.04%)

 < 0.01

 Atrial flutter

705 (7.03%)

891 (8.24%)

 < 0.01

 Ventricular fibrillation

234 (2.33%)

195 (1.8%)

0.01

 Ventricular flutter

0 (0%)

2 (0.02%)

0.50

 Sick sinus syndrome

227 (2.26%)

251 (2.32%)

0.78

 First-degree atrioventricular block

327 (3.26%)

500 (4.62%)

 < 0.01

 Second-degree atrioventricular block

97 (0.97%)

118 (1.09%)

0.41

 Complete atrioventricular block

749 (7.47%)

1449 (9.53%)

 < 0.01

 Carotid artery disease

8 (0.08%)

5 (0.05%)

0.41

 Hyperlipidemia

5313 (52.98%)

6418 (59.37%)

 < 0.01

 Anemia

506 (5.05%)

286 (2.65%)

 < 0.01

 Thrombocytopenia

2881 (28.73%)

3604 (33.34%)

 < 0.01

 Sleep apnea

1512 (15.08%)

1866 (17.26%)

 < 0.01

 Tobacco use

4439 (44.26%)

3895 (36.03%)

 < 0.01

 Previous MI

569 (5.67%)

423 (3.91%)

 < 0.01

 Previous CVA

570 (5.68%)

640 (5.92%)

0.48

 Previous CABG

377 (3.76%)

315 (2.91%)

 < 0.01

 Previous PCI

643 (6.41%)

642 (5.94%)

0.16

 Previous valve replacement

350 (3.49%)

366 (3.39%)

0.70

  1. APR-DRG All patients refined diagnosis related groups, CABG coronary artery bypass grafting, CVA cerebrovascular accident, MI myocardial infarction, PCI percutaneous coronary intervention, SES socioeconomic status, SAVR surgical aortic valve replacement.