Table 2 Comparison of immune parameters and disease activity measures between non-spiritual and spiritual subgroups.

From: Spirituality is associated with immune parameters and disease activity in primary Sjögren’s syndrome: a cross-sectional study

 

Non-spiritual (n = 48)

Spiritual (n = 60)

p-value

Average (95%CI)

IGG

14.45 (12.54–16.35)

14.58 (12.28–6.88)

0.654

RF

49.90 (14.24–85.55)

30.57 (16.01–45.12)

0.371

SSA

46.92 (36.41–57.42)

42.43 (33.47–51.40)

0.559

SSB

36.48 (25.89–47.07)

27.05 (19.24–34.86)

0.289

ESSDAI

2.88 (1.97–3.78)

2.18 (1.10–3.27)

0.010*

ESSPRI score

5.35 (4.74–5.95)

4.97 (4.30–5.64)

0.445

ESSPRI main items (1–3)

dryness (ESSPRI01)

5.46 (4.82–6.10)

5.29 (4.66–5.92)

0.847

fatigue (ESSPRI02)

5.67 (4.92–6.41)

4.93 (4.17–5.69)

0.186

limb pain (ESSPRI03)

4.92 (4.04–5.79)

5.03 (4.19–5.88)

0.902

ESSPRI items 4–10

mental fatigue (ESSPRI04)

2.64 (1.99–3.28)

3.20 (2.52–3.89)

0.348

ESSPRI dryness items

ocular (ESSPRI05)

5.28 (4.52–6.04)

5.03 (4.37–5.69)

0.564

oral (ESSPRI06)

4.89 (4.05–5.74)

5.54 (4.84–6.24)

0.233

skin (ESSPRI07)

5.06 (4.39–5.74)

4.63 (3.88–5.38)

0.398

nasal (ESSPRI08)

3.46 (2.61–4.31)

3.71 (2.96–4.46)

0.634

tracheal (ESSPRI09)

3.70 (2.86–4.55)

3.98 (3.20–4.77)

0.633

vaginal (ESSPRI10)

3.51 (2.54–4.49)

2.13 (1.41–2.85)

0.041*

  1. Confidence interval level of 95% was applied.
  2. IGG immunoglobulin G, RF rheumatoid factor, SSA anti-Ro/SSA autoantibody, SSB anti-La/SSB autoantibody, ESSDAI EULAR Sjögren’s syndrome disease activity index, ESSPRI EULAR Sjögren’s syndrome patient reported index (ESSPRI), CI confidence interval.
  3. *p < 0.05; **p < 0.01.
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