Table 4 Biochemical parameters levels in different ACE I/D genotypes in diabetic patient and normal control groups.

From: Potential role of serum copeptin among smoker T2DM patients with emphasis to ACE I/D gene polymorphism predicting DN

Parameters

DD

ID

II

Diabetic patient n = 42)

Normal control (n = 52)

Diabetic patient (n = 50)

Normal control (n = 42)

Diabetic patient (n = 14)

Normal control (n = 8)

Fasting s. glucose (mg/dL

167.57 ± 97.00

93.25 ± 19.85

164.00 ± 77.10

85.48 ± 22.37

161.71 ± 76.85

97.38 ± 13.46

P value

 < 0.001

 < 0.001

< 0.031

HbA1C (%)

7.09 ± 1.16

5.22 ± 0.73

7.66 ± 1.68

5.28 ± 0.60

6.87 ± 1.18

5.21 ± 0.59

P value

 < 0.001

 < 0.001

 < 0.017

Serum KIM-1 (ng/mL)

30.86 ± 16.39

24.81 ± 8.54

30.76 ± 14.29

24.25 ± 8.18

27.71 ± 8.2

24.85 ± 7.08

P value

< 0.023

< 0.011

0.42

Serum Copeptin (ng/mL)

599.84 ± 154.4

497.73 ± 109.51

541.46 ± 98.84

447.58 ± 85.07

549.71 ± 84.28

448.71 ± 116.43

P value

 < 0.001

 < 0.001

0.07

Serum Chol (mg/dL)

181.0 ± 48.0

134.0 ± 42.0

175.83 ± 43.37

136.50 ± 45.04

186.0 ± 56.36

108.14 ± 19.51

P value

 < 0.001

 < 0.001

 < 0.002

Serum TG (mg/mL)

190.95 ± 68.69

124.91 ± 59.17

191.70 ± 60.57

151.31 ± 73.51

233.14 ± 125.46

149.0 ± 72.81

P value

 < 0.001

< 0.01

0.12

uPb (ng/mg creat)

0.23 ± 0.30

0.20 ± 0.14

0.41 ± 0.53

0.17 ± 0.15

0.32 ± 0.15

0.22 ± 0.11

P value

0.59

 < 0.032

0.21

eGFR (mL/min/1.73m2)

115.53 ± 45.30

131.50 ± 24.17

118.78 ± 36.59

135.45 ± 27.67

137.64 ± 37.93

122.0 ± 27.57

P value

 < 0.038

 < 0.019

0.31

Back to article page