Figure 7 | Scientific Reports

Figure 7

From: Integration of single-cell sequencing and bulk RNA-seq to identify and develop a prognostic signature related to colorectal cancer stem cells

Figure 7

Functional analysis of the prognostic risk model. (A) Results of GO functional enrichment analysis showed (P < 0.05, R = 1) that the biological processes of the risk model are active in the Wnt pathway, the cellular fractions are enriched in collagen-containing extracellular matrix, and the molecular functions are active in signaling receptor activator activities. (B) Showing the corresponding circle diagrams. (C) and (D) show the Hallmark enrichment analysis of the patients of high-risk group and the patients of low-risk group, respectively. As a result, high-risk patients were mainly enriched for EMT process, and low-risk patients were negatively correlated with E2F activity.

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