Table 1 Summary of patient variables and tumour clinicopathological variables, detailing histology, molecular subtype, stage, grade, and patient age.

From: An optimised patient-derived explant platform for breast cancer reflects clinical responses to chemotherapy and antibody-directed therapy

Characteristic

Number (%) of patients/tumours

Number of patients

55

Age

 Median

66.5

 Range

35–87

Histology

 Ductal

28 (50.9)

 Lobular

8 (145)

 Mucinous

7 (12.7)

 Mixed

12 (21.8)

Subtypes

 Luminal A/Normal Like

36 (6.45

 Luminal B

7 (12.7)

 TNBC

8 (14.5)

 HER2- Enriched

4 (7.3)

Stage

 IA

1 (1.9)

 IB

2 (3.7)

 IIA

24 (44.4)

 IIB

11 (20.4)

 IIIA

15 (27.8)

 IIIB

1 (1.9)

Grade

 1

2 (3.7)

 2

29 (53.7)

 3

23 (42.6)

Neo-adjuvant therapy

 Yes

7 (12.7)

 No

48 (87.3)

  1. Clinical data, histology, stage, and grade were provided from histopathologic reports submitted by consultant pathologists at University Hospitals of Leicester, Leicester, UK. Stage/Grade information was unavailable for 1 patient sample.