Figure 4 | Scientific Reports

Figure 4

From: CILP2 is a potential biomarker for the prediction and therapeutic target of peritoneal metastases in colorectal cancer

Figure 4

The small interfering RNA-mediated knockdown of CILP2 inhibiting the proliferation, colony formation, migration, invasion, and adhesion of HCT116 cells in vitro. (a) The knockdown of CILP2 decreased cell proliferation. (b) The knockdown of CILP2 decreased colony formation. (c) The knockdown of CILP2 significantly decreased cell migration and invasion. (d) The knockdown of CILP2 inhibited epithelial-mesenchymal transition markers and transcription factors in HCT116 cells. (e) The relative expression of each protein is determined as a ratio to β-actin. Each experiment is repeated at least three times. All data are expressed as the mean ± standard deviation; *P < 0.05.

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