Table 1 Association between the CILP2 mRNA expression and clinicopathological characteristics of the patients included in the validation cohort.

From: CILP2 is a potential biomarker for the prediction and therapeutic target of peritoneal metastases in colorectal cancer

Variables

High CILP2 (n = 42)

Low CILP2 (n = 74)

P value*

Age (years), mean ± SD

59.50 ± 10.49

59.26 ± 11.93

0.91

Sex

0.44

 Male

23 (55%)

46 (62%)

 

 Female

19 (45%)

28 (38%)

 

Preoperative CEA, ng/mL

0.15

 ≤ 5

24 (57%)

53 (72%)

 

 > 5

18 (43%)

21 (28%)

 

Peritoneal metastases

0.00008

 Negative

21 (50%)

63 (85%)

 

 Positive

21 (50%)

11 (15%)

 

Liver metastases

0.51

 Negative

30 (71%)

57 (77%)

 

 Positive

12 (29%)

17 (23%)

 

Lung metastases

0.17

 Negative

33 (79%)

66 (89%)

 

 Positive

9 (21%)

8 (11%)

 

Differentiation

0.02

 Differentiated

32 (76%)

69 (93%)

 

 Undifferentiated

10 (24%)

5 (7%)

 

AJCC stage

0.02

 I

0 (0%)

1 (1%)

 

 II

9 (21%)

31 (42%)

 

 III

11 (26%)

23 (31%)

 

 IV

22 (52%)

19 (26%)

 
  1. Bold number in the P value: the variables were considered to have statistical significance as P value ≤ 0.05.
  2. SD, Standard deviation; CEA, Serum carcinoembryonic antigen; AJCC, American Joint Committee on Cancer, Differentiated, Well-differentiated and moderately differentiated; Undifferentiated, Poorly differentiated, undifferentiated.
  3. *Comparison of validation cohort by χ2 test or unpaired t-test.