Figure 4
From: Cell adhesion molecule CD44 is dispensable for reactive astrocyte activation during prion disease
Astrocyte morphological assessment in CD44-deficient mice. (A) Representative images from GFAP immunostained Dentate Gyrus molecular layer of naïve, 140 dpi or terminal prion infected WT and CD44−/− mice. Scale bar = 20 µm. Total number of (B) branches, (C) segments, (D) terminal points and (E) Sholl intersections as determined by Imaris filament tracing. Points represent individual mice, bar = group mean. ANOVA with Sidak’s multiple comparison test. *P < 0.05; **P < 0.005.
