Figure 6
From: Cell adhesion molecule CD44 is dispensable for reactive astrocyte activation during prion disease
Microglial responses to CNS prion disease. (A) Representative images from Aif1 immunostained hippocampus CA1 of naïve, 140 dpi or terminal prion infected WT and CD44−/− mice. Scale bar = 100 µm. (B) Quantitation of % area coverage of Aif1 staining. (C) RT-qPCR analysis of Aif1 gene expression. RT-qPCR analysis of (D) Tnf, (E) Il1b and (F) Tgfb, (G) Il6 gene expression. Points represent individual mice, bar = group mean. ANOVA with Sidak’s multiple comparison test.
