Table 1 IC50 values in T98G cells of crude/chemically modified extracts and pure compounds.

From: Enhancing structural diversity through chemical engineering of Ambrosia tenuifolia extract for novel anti-glioblastoma compounds

 

IC50

R2

Extract

ATG

10.8 μg/mL

0.705

ATD

7.9 μg/mL

0.566

Compound

PsiA

17.4 μM

0.837

PsiB

13.9 μM

0.807

PsiC

14.2 μM

0.790

(3)

13.6 μM

0.743

Standard treatment

Temozolomide

844.0 μM

0.960

  1. GraphPad Prism software was used to calculate the IC50 (half maximal inhibitory concentration) value of each extract or compound. R2 value indicate how well the experimental data fit the regression model.
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