Table 4 Regression analysis of factors for the prediction of a cumulative live birth for the fresh plus all frozen embryo transfer cycles.

From: The cumulative live birth rate and cost-effectiveness of the clomiphene and gonadotropin cotreatment protocol versus the mid-luteal GnRH agonist protocol in women over 35 years old

Factors predicting a cumulative live birth

Coefficient(B)

S.E

Wald (χ2)

P value

Hazard ratio (95% CI)

Maternal age

− 0.135

0.039

11.877

0.001

0.874 (0.809–0.943)

Type of infertility

 Primary infertility

    

1

 Secondary infertility

− 0.052

0.198

0.069

0.794

0.949 (0.644–1.400)

Infertility duration

0.000

0.022

0.000

0.988

1.000 (0.958–1.043)

Cycle number

 The first cycle

    

1

 The second cycle

0.084

0.200

0.175

0.676

1.087 (0.734–1.610)

Treatment protocol

 GnRHa

    

1

 CC cotreatment

0.388

0.201

3.725

0.084

1.475 (0.994–2.187)

Body mass index

0.000

0.000

0.160

0.689

1.000 (1.00–1.00)

Basal FSH

0.026

0.035

0.545

0.461

1.026 (0.958–1.098)

AMH

0.116

0.041

18.77

 < 0.001

1.112 (1.017–1.431)

Total Gn dosage

0.000

0.000

0.570

0.450

1.000 (1.00–1.00)

Days of stimulation

− 0.106

0.073

2.102

0.147

0.900 (0.780–1.038

No. of oocytes retrieved

0.023

0.020

1.378

0.240

1.023 (0.985–1.063)

No. of available embryos

0.352

0.050

50.517

 < 0.001

1.422 (1.290–1.567)

Cause of infertility

 Tubal

    

1

 Male factor

0.439

0.307

2.043

0.153

1.551 (0.850–2.830)

 Anovulatory

− 0.460

0.456

1.017

0.313

0.631 (0.258–1.543)

 Unexplained

0.087

0.210

0.173

0.678

1.091 (0.723–1.657)

 Diminished ovarian reserve

0.055

0.308

0.032

0.857

1.057 (0.578–1.933)

 Endometriosis

0.371

0.420

0.782

0.376

1.449 (0.637–3.298)

 Mixed

0.689

0.741

0.865

0.352

1.991 (0.466–8.506)

  1. CC cotreatment clomiphene citrate and gonadotropin cotreatment, GnRHa gonadotropin-releasing hormone agonist, FSH follicle-stimulating hormone, AMH anti-müllerian hormone, Gn gonadotropin, CI confidence interval.