Table 2 Cytotoxicity testing of the selected compounds compared to PZQ.

From: A reanalysis and integration of transcriptomics and proteomics datasets unveil novel drug targets for Mekong schistosomiasis

Compound

CC50 (µM)

PZQ

157.3 ± 5.1

FAK inhibitor 14

11.2 ± 1.1

PF-03814735

7.6 ± 0.4

  1. CC50 indicates the 50% cytotoxic concentration of the chemical compound against the HepG2 cell line. Results are reported as mean ± S.E