Table 2 Clinical and biochemical characteristics of the study subjects with or without liver fibrosis.
From: Association between the cardiometabolic index and NAFLD and fibrosis
Normal | Liver fibrosis | |||
|---|---|---|---|---|
Total | < 8.2kPa (n = 2721) | ≥ 8.2kPa (n = 275) | P | |
CMI [M (P25, P75)] | 0.46 (0.25,0.81) | 0.44 (0.24,0.77) | 0.73 (0.43,1.11) | < 0.001# |
CMI quartile | ||||
Q1 (≤ 0.25) | 749 (25.00) | 724 (26.61) | 25 (9.09) | < 0.001 |
Q2 (0.25 ~ 0.46) | 749 (25.00) | 698 (25.65) | 51 (18.55) | |
Q3 (0.46 ~ 0.81) | 749 (25.00) | 676 (24.84) | 73 (26.55) | |
Q4 (> 0.81) | 749 (25.00) | 623 (22.90) | 126 (45.82) | |
Sex | ||||
Men | 1355 (45.23) | 1209 (44.43) | 146 (53.09) | < 0.001 |
Women | 1641 (54.77) | 1512 (55.57) | 129 (46.91) | |
Age [M (P25, P75)] | 51.0 (35.0,64.0) | 50.0 (34.0,63.0) | 58.0 (43.0,67.0) | < 0.001# |
BMI [M (P25, P75)] | 28.6 (24.7,33.5) | 28.1 (24.5,32.6) | 35.8 (29.3,42.0) | < 0.001# |
Race | ||||
Mexican American | 391 (13.05) | 346 (12.72) | 45 (16.36) | < 0.001 |
Other Hispanic | 310 (10.35) | 283 (10.40) | 27 (9.82) | |
Non-Hispanic white | 993 (33.14) | 892 (32.78) | 101 (36.73) | |
Non-Hispanic black | 739 (24.67) | 676 (24.84) | 63 (22.91) | |
Other race—Including multi-racial | 563 (18.79) | 524 (19.26) | 39 (14.18) | |
Smoke | ||||
Yes | 1121 (37.44) | 1004 (36.93) | 117 (42.55) | < 0.001 |
No | 1873 (62.56) | 1715 (63.07) | 158 (57.45) | |
Diabetes | ||||
Yes | 448 (14.96) | 337 (12.39) | 111 (40.36) | < 0.001 |
No | 2546 (85.04) | 2382 (87.61) | 164 (59.64) | |
Hypertension | ||||
Yes | 1099 (36.74) | 941 (34.65) | 158 (57.45) | < 0.001 |
No | 1892 (63.26) | 1775 (65.35) | 117 (42.55) | |
TG (mmol/L) [M (P25, P75)] | 1.01 (0.68,1.50) | 0.98 (0.67,1.49) | 1.22 (0.85,1.75) | < 0.001# |
TC (mmol/L) [M (P25, P75)] | 4.68 (4.06,5.40) | 4.71 (4.11,5.43) | 4.37 (3.78,5.15) | < 0.001# |
HDL (mmol/L) [M (P25, P75)] | 1.32 (1.09,1.60) | 1.34 (1.11,1.63) | 1.16 (1.03,1.40) | < 0.001# |
LDL (mmol/L) [M (P25, P75)] | 2.77 (2.20,3.36) | 2.77 (2.22,3.39) | 2.48 (1.94,3.23) | < 0.001# |
AST(IU/L) [M (P25, P75)] | 19.0 (15.0,23.0) | 19.0 (15.0,23.0) | 21.0 (17.0,29.0) | < 0.001# |
ALT (IU/L) [M (P25, P75)] | 17.0 (13.0,25.0) | 17.0 (12.0,24.0) | 23.0 (15.0,35.0) | < 0.001# |
GGT(IU/L) [M (P25, P75)] | 21.0 (15.0,30.0) | 20.0 (14.0,29.0) | 30.0 (20.0,54.0) | < 0.001# |
ALB(g/L) [M (P25, P75)] | 40.0 (38.0,42.0) | 40.0 (38.0,42.0) | 39.0 (37.0,42.0) | < 0.001# |
BUN (mmol/L) [M (P25, P75)] | 5.0 (3.9,6.1) | 5.0 (3.9,6.1) | 5.4 (4.3,6.8) | < 0.001# |
Cr(mmol/L) [M (P25, P75)] | 73.4 (61.9,86.6) | 73.4 (61.9,86.6) | 75.1 (62.8,90.2) | < 0.001# |
TB (umol/L) [M (P25, P75)] | 6.8 (5.1,10.3) | 6.8 (5.1,10.3) | 8.6 (5.1,10.3) | < 0.001# |
UA (umol/L) (̅x ± s) | 321.9 ± 85.3 | 318.6 ± 84.6 | 354.2 ± 84.6 | < 0.001 |
